SPRAVATO® Treatment Center For Southern Illinois

What is SPRAVATO® or Esketamine?

Similar to intravenous ketamine, nasal Esketamine operates through the glutamate neural pathway, enhancing levels of glutamate in the brain to alleviate symptoms in patients with Treatment Resistant Depression. The positive aspect is that Esketamine / Spravato® is widely covered by most insurances, offering accessibility and potential relief to those who need it. This breakthrough treatment represents a promising option for individuals seeking effective relief from the challenges of Treatment Resistant Depression (TRD).

The Albany Clinic in Carbondale Illinois specializes in SPRAVATO® esketamine nasal-spray treatment.

SPRAVATO® is a registered trademark of Johnson & Johnson and its affiliated companies

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a woman is standing on a balcony overlooking mountains with her arms outstretched
a nasal spray bottle is sitting on a white surface with the title of Spravato®

How SPRAVATO® Treatment Works

Spravato® is a prescription medication brand designed for treatment-resistant depression (when two or more traditional methods are ineffective) and for managing suicidal thoughts for adults with Major Depressive Disorder (MDD). This nasal spray medication has the potential to alleviate depression symptoms in just a few hours which makes it a sought after treatment for depression when time to relief is critical.

Spravato® elevates an individual's glutamate levels, which is the brain's most prevalent chemical messenger. Due to its wide-reaching effects, the glutamatergic system has a greater impact on multiple cells simultaneously. The primary component of Spravato® (esketamine) is recognized for fostering synapses between brain cells which are often lacking in individuals dealing with depression. By influencing more cells at once, these connections are more likely to elicit the full effects of the medication.

SPRAVATO® is often used for rapid relief from depression, transcending traditional timelines of typical treatment options. Although it is in the form of a nasal spray, only certain mental health facilities (SPRAVATO® REMS) can offer this treatment option.

SPRAVATO® helped Nicole’s treatment-resistant depression. Now, she’s resuming her education and sharing her story.

Do NOT take SPRAVATO® if any of the following applies to you:

  • You have a blood vessel disease (aneurysm)
  • You have an abnormal connection between your blood vessels (arteriovenous malformation)
  • You have a history of bleeding in the brain
  • You are allergic to esketamine or a similar medicine called ketamine used for anesthesia or any of the other ingredients in SPRAVATO®

Be sure to tell your healthcare provider if:

  • You have heart, brain or liver problems
  • You have ever had psychosis (see, feel, or hear things that aren't there, or believe in things that aren't true)
  • You are pregnant or breastfeeding. You should not take SPRAVATO® if you are pregnant or breastfeeding
  • You are taking prescription or over-the-counter medicines, including vitamins or herbal supplements
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SPRAVATO® is only available at a REMS certified SPRAVATO® treatment center under the supervision of a healthcare provider.

What Do Our Patients Say About Receiving Treatment at The Albany Clinic?

Clatus Bierman

Safe, professional and individualized experience.  Doctor and staff are very knowledgeable and responsive to your questions and concerns; making treatment experience exceptional.  Highly recommend for those who have searched for options.

Tammi Pinski

From the moment I spoke with Sylvia I knew I was in good hands.  After my initial consultation with Dr. Garwin, meeting the nursing staff (❤️)  and receiving an IV infusion, I experienced IMMEDIATE  relief.

Hunter Clark

Dr Garwin and his staff helped me when I didn’t think there was anything left to try. The Albany clinic has changed my life.

  • How is SPRAVATO® different?

    SPRAVATO® targets the N-methyl-Daspartate (NMDA) receptor and is believed to work differently than currently available oral antidepressants. The exact way that SPRAVATO® works is unknown.

  • Can I receive treatment at home?

    No.  SPRAVATO® is only available at certified SPRAVATO® treatment centers under the supervision of a healthcare provider who will:


    • Determine if SPRAVATO® is right for you

    • Discuss your full medical and depression treatment history with you.

  • How often will I receive treatment?

    After four weeks and twice weekly sessions or doses, you and Dr. Garwin at The Albany Clinic will determine if continued treatment with SPRAVATO® is necessary. Treatment beyond four weeks is not typical.

  • What should I expect on treatment days?

    You will not be able to drive, so plan transportation on treatment days. You will administer the nasal spray yourself under the supervision of Dr. Garwin and will be monitored for side effects for at least two hours. The Albany Clinic staff will let you know when it’s okay to leave. It's important not to drive, operate machinery or do anything where you need to be completely alert until the day after your treatment session, following a restful sleep.

  • What should I know about the side effects of SPRAVATO®?

    Here are the most common side effects:


    • Dissociation

    • Dizziness

    • Nausea

    • Feeling sleepy

    • Spinning sensation

    • Numbness

    • Feeling anxious

    • Lack of energy

    • Increased blood pressure

    • Vomiting

    • Feeling drunk

    • Feeling very happy or excited


    If these common side effects occur, they usually happen right after taking SPRAVATO® and go away the same day.


    Complete side effects are further documented here (click for PDF).

Looking for a SPRAVATO® treatment center near Carbondale Illinois?  You found it!

Your initial consultation is free of charge. Schedule yours today!

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